QUÁ TUYỆT THẦY - Bài giảng tại PCTU

From: Dr Tung <tung.nguyen@pctu.edu.vn>

Date: Sun, Nov 1, 2020 at 9:39 PM

Subject: RE: USMLE step 1 Secrets: Chương 6 (tham khảo 1)

To: Bùi Duy Tâm <buiduytam1@gmail.com>, Vân Phạm Hùng <van.pham@pctu.edu.vn>,

QUÁ TUYỆT THẦY.

EM ĐÃ CHUYỂN THÔNG TIN NẦY ĐẾN NƠI CẦN PHẢI NHẬN RỒI THẦY.

EM CŨNG CHO CÔ HẠNH MUA 1 CUỐN SÁCH HỌC THEO CHƯƠNG TRÌNH USLME 1, SÁCH GIẤY VÀ ONLINE ĐỂ LÀM NGUỒN TÀI LIỆU CHO THƯ VIỆN BÙI DUY TÂM RỒI, HY VỌNG CÁC THẦY CỦA TRƯỜNG,  BS CỦA BVTT VÀ SINH VIÊN Y KHOA PCTU CÙNG CÓ KHÁI NIỆM VỀ USLME VÀ CÙNG THAM KHẢO VÀ SOẠN BÀI.

CÁM ƠN THẦY.

From: Bùi Duy Tâm [mailto:buiduytam1@gmail.com]

Sent: Sunday, November 1, 2020 8:17 AM

To: Tam Bui <buiduytam1@gmail.com>; 18yk1@pctu.edu.vn; Dr. Tung <tung.nguyen@pctu.edu.vn>; Vân Phạm Hùng <van.pham@pctu.edu.vn>;

Subject: USMLE step 1 Secrets: Chương 6 (tham khảo 1) 

Natriuresis is the process of sodium excretion in the urine through the action of the kidneys. It is promoted by ventricular and atrial natriuretic peptides as well as calcitonin, and inhibited by chemicals such as aldosterone. Natriuresis lowers the concentration of sodium in the blood and also tends to lower blood volume because osmotic forces drag water out of the body's blood circulation and into the urine along with the sodium. Many diuretic drugs take advantage of this mechanism to treat medical conditions like hypernatremia and hypertension, which involve excess blood volume. 

 

In disseminated intravascular coagulation, abnormal clumps of thickened blood (clots) form inside blood vessels. These abnormal clots use up the blood's clotting factors, which can lead to massive bleeding in other places. Causes include inflammation, infection, and cancer.

Symptoms include blood clots and bleeding, possibly from many sites in the body.

The goal is to treat the underlying cause and provide supportive care through intravenous fluids and blood transfusions.

 

The signs and symptoms of ARDS can vary in intensity, depending on its cause and severity, as well as the presence of underlying heart or lung disease. They include:

·       Severe shortness of breath

·       Labored and unusually rapid breathing

·       Low blood pressure

·       Confusion and extreme tiredness

ARDS usually follows a major illness or injury, and most people who are affected are already hospitalized.


Causes

Bronchioles and alveoliOpen pop-up dialog box

The mechanical cause of ARDS is fluid leaked from the smallest blood vessels in the lungs into the tiny air sacs where blood is oxygenated. Normally, a protective membrane keeps this fluid in the vessels. Severe illness or injury, however, can cause damage to the membrane, leading to the fluid leakage of ARDS.

Underlying causes of ARDS include:

·       Sepsis. The most common cause of ARDS is sepsis, a serious and widespread infection of the bloodstream.

·       Inhalation of harmful substances. Breathing high concentrations of smoke or chemical fumes can result in ARDS, as can inhaling (aspirating) vomit or near-drowning episodes.

·       Severe pneumonia. Severe cases of pneumonia usually affect all five lobes of the lungs.

·       Head, chest or other major injury. Accidents, such as falls or car crashes, can directly damage the lungs or the portion of the brain that controls breathing.

·       Coronavirus disease 2019 (COVID-19). People who have severe COVID-19 may develop ARDS.

·       Others. Pancreatitis (inflammation of the pancreas), massive blood transfusions and burns.


Myasthenia gravis

Also called: MG

 


Description

A weakness and rapid fatigue of certain muscles under voluntary control.

The condition is caused by a breakdown in communication between nerves and muscles.

Symptoms include weakness in the arm and leg muscles, double vision, and difficulties with speech and chewing.

Medications, therapy, and surgery can help.

 

Achalasia is a primary esophageal motility disorder characterized by the absence of esophageal peristalsis and impaired relaxation of the lower esophageal sphincter (LES) in response to swallowing. The LES is hypertensive in about 50% of patients. These abnormalities cause a functional obstruction at the gastroesophageal junction (GEJ). 

 

 Misoprostol, sold under the brandname Cytotec among others, is a medication used to prevent and treat stomach ulcers, start labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus. For abortions it is used by itself and with mifepristone or methotrexate. By itself, effectiveness for abortion is between 66% and 90% Misoprostol is taken by mouth when used to prevent gastric ulcers in persons taking NSAIDs For labor induction or abortion, it is taken by mouth, dissolved in the mouth, or placed in the vagina. For postpartum bleeding it may also be used rectally.

Common side effects include diarrhea and abdominal pain.It is a prostaglandin analogue specifically, a synthetic prostaglandin E1, PGE1

The prostaglandins are a group of lipids made at sites of tissue damage or infection that are involved in dealing with injury and illness. They control processes such as inflammation, blood flow, the formation of blood clots and the induction of labour.  


Celiac disease 

Description

An immune reaction to eating gluten, a protein found in wheat, barley, and rye.

Over time, the immune reaction to eating gluten creates inflammation that damages the small intestine's lining, leading to medical complications. It also prevents absorption of some nutrients (malabsorption).

The classic symptom is diarrhea. Other symptoms include bloating, gas, fatigue, low blood count (anemia), and osteoporosis. Many people have no symptoms.

The mainstay of treatment is a strict gluten-free diet that can help manage symptoms and promote intestinal healing.

 

Curling's ulcer is an acute gastric erosion resulting as a complication from severe burns when reduced plasma volume leads to ischemia and cell necrosis (sloughing) of the gastric mucosa

These stress ulcers (actually shallow multiple erosions) were once a common complication of serious burns, presenting in over 10% of cases, and especially common in child burn victims. They result in perforation and hemorrhage more often than other forms of intestinal ulceration and had correspondingly high mortality rates (at least 80%).

While emergency surgery was once the only treatment, combination therapies including enteral feeding with powerful antacids such as H2-receptor antagonists or, more recently, proton pump inhibitors such as omeprazole have made Curling's ulcer a rare complication.

Cushing's ulcer is a gastro-duodenal ulcer produced by elevated intracranial pressure caused by an intracranial tumor, head injury or other space-occupying lesion.

 stress ulcers: found in the areas of the digestive tract (e.g., stomach, esophagus)